105 Marathons in 105 Days.What an astonishing guy you are Neil O'Maonaigh-Lennon!

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105 Marathons in 105 Days would be an astonishing achievement anytime, but to complete it in the weather that we have had for the last few weeks is beyond belief!.What an absolutely gob smackingly amazing thing Neil has done!.

Teacher Neil (30) set off from Brighton on the 10th September....and has run every day since then finishing his "Marathon" effort today. He has embarked upon this wonderful fundraiser to raise money for Cancer Research. Neil says it is a cause very close to his own heart as he lost 2 of his grandparents to the disease whilst he was a child.

If there is any justice in this world then this man will be getting a medal from the Queen in the not too distant future for his super human efforts.

Neil O'Maonaigh-Lennon, you are a superstar in the charity fundraising circles, well done to you sir, and may I just take this opportunity to wish you and your family a very Peaceful and restful Christmas. Now, why don't you put your feet up and congratulate yourself on a truly inspiring achievement....you,of all people,deserve it!. :-)

If you would like to sponsor Neil please click HERE to visit his Justgiving site.

Amazing :-)

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Please support my Cousin in his BUPA charity run this Sunday

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My cousin Darren Ward is taking part in the BUPA Great South Run on Sunday this week. Please make a donation to his JustGiving page. He lost both his grand parents to Cancer and is raising money for Cancer Research.

To donate follow this Link by clicking HERE

Thanks :-)

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Missing 'silencer' could possibly trigger leukaemia

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Sunday 11 July 2010

Cancer Research UK Press Release

A completely new mechanism that leads to the development of a certain type of leukaemia could eventually be targeted by new treatments, according to research published in Nature Immunology today (Sunday)1.

Researchers, funded by Cancer Research UK, the BBSRC and the Medical Research Council, discovered that when two genes are missing from mice they develop an aggressive form of leukaemia, similar to acute lymphoblastic leukaemia2 in humans.

The two genes produce ‘silencer’ proteins that normally neutralise a group of cell messengers once they have successfully delivered their message to the cell’s machinery responsible for growth.

Without the ‘silencer’ proteins the messenger continues to deliver its message without any control. In this research the target messenger controls the production of a protein called Notch1, which plays a key role in the development of a type of white blood cell. Without the silencers, higher levels of Notch1 are produced than is needed for normal growth, causing the cells to grow out of control, leading to leukaemia.

To see the full report click HERE to view the Cancer Research Website.

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